This is an exasperated Japanese voice clip where someone's basically saying "What?! Ugh, seriously?! Not again?!" It's got that dramatic, over-the-top anime energy that works great for reaction memes or when you need a character to sound frustrated and done with everything.
なんだよ！もぉぉぉ！またかよぉぉぉ！ Sound Effect
Shared by Krabby